3-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE
3-Fluoro-4-(trifluoromethyl)benzyl bromide
CAS: 213203-65-7
Molecular Formula: C8H5BrF4
3-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE - Names and Identifiers
3-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE - Physico-chemical Properties
| Molecular Formula | C8H5BrF4 |
| Molar Mass | 257.02 |
| Density | 1.640±0.06 g/cm3(Predicted) |
| Melting Point | 25-27°C |
| Boling Point | 206.8±35.0 °C(Predicted) |
| Flash Point | 102.2°C |
| Vapor Presure | 0.334mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Sensitive | Lachrymatory |
| Refractive Index | 1.472 |
| MDL | MFCD00236289 |
3-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE - Risk and Safety
| Risk Codes | R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 1760 |
| Hazard Note | Corrosive/Lachrymatory |
| Hazard Class | 8 |
| Packing Group | III |
3-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE - Introduction
3-Fluoro-4-(trifluoromethyl)benzyl bromide is an organic compound with the chemical formula C8H5BrF4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular weight: 257.03g/mol
-Melting point:-20 ° C
-Boiling Point: 115 ° C (760 mmHg)
-Density: 1.789g/cm³
-Solubility: Soluble in organic solvents such as ether, acetone and chloroform
Use:
- 3-Fluoro-4-(trifluoromethyl)benzyl bromide is an important organic synthesis intermediate, commonly used in the synthesis of pesticides, pharmaceuticals and other organic compounds.
-It can be used as a protecting group for Styrene (aromatic alcohol) for organic synthesis reactions.
Method:
3-Fluoro-4-(trifluoromethyl)benzyl bromide can be prepared by the following steps:
1. At low temperature, 3-fluoro-4-chlorobenzyl alcohol and Trifluoromethyl bromide are reacted in the presence of sodium carbonate.
2. After reduction treatment with sodium sulfite or cuprous chloride, the target product is obtained.
Safety Information:
- 3-Fluoro-4-(trifluoromethyl)benzyl bromide is an organic compound and should be operated under suitable laboratory conditions.
-It may be irritating to the eyes, skin and respiratory tract and direct contact should be avoided.
-Observe safe practices and wear appropriate protective equipment, such as goggles and gloves, during handling and storage.
-Disposal of waste should be carried out in accordance with local regulations and should not be dumped.
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular weight: 257.03g/mol
-Melting point:-20 ° C
-Boiling Point: 115 ° C (760 mmHg)
-Density: 1.789g/cm³
-Solubility: Soluble in organic solvents such as ether, acetone and chloroform
Use:
- 3-Fluoro-4-(trifluoromethyl)benzyl bromide is an important organic synthesis intermediate, commonly used in the synthesis of pesticides, pharmaceuticals and other organic compounds.
-It can be used as a protecting group for Styrene (aromatic alcohol) for organic synthesis reactions.
Method:
3-Fluoro-4-(trifluoromethyl)benzyl bromide can be prepared by the following steps:
1. At low temperature, 3-fluoro-4-chlorobenzyl alcohol and Trifluoromethyl bromide are reacted in the presence of sodium carbonate.
2. After reduction treatment with sodium sulfite or cuprous chloride, the target product is obtained.
Safety Information:
- 3-Fluoro-4-(trifluoromethyl)benzyl bromide is an organic compound and should be operated under suitable laboratory conditions.
-It may be irritating to the eyes, skin and respiratory tract and direct contact should be avoided.
-Observe safe practices and wear appropriate protective equipment, such as goggles and gloves, during handling and storage.
-Disposal of waste should be carried out in accordance with local regulations and should not be dumped.
Last Update：2024-04-09 02:00:44
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View History
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